Effects of interstrain renal transplantation on NaCl-induced hypertension in Dahl rats.

  title={Effects of interstrain renal transplantation on NaCl-induced hypertension in Dahl rats.},
  author={Donald A Morgan and Gerald F Dibona and Allyn L. Mark},
  volume={15 4},
Previous studies using renal transplantation suggested that the genotype of a homograft kidney plays the primary role in determining chronic arterial pressure levels in Dahl salt-sensitive (DS) and salt-resistant (DR) rats, but this conclusion derived largely from observations during low NaCl diet. Recent studies indicate that extrarenal factors, including the sympathetic nervous system, play a critical role in the development of NaCl-induced hypertension in DS rats. To assess the contribution… CONTINUE READING


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