Effects of intermittent lower limb ischaemia on coronary blood flow and coronary resistance in pigs.

@article{Shimizu2007EffectsOI,
  title={Effects of intermittent lower limb ischaemia on coronary blood flow and coronary resistance in pigs.},
  author={Mikiko Shimizu and Igor E. Konstantinov and Rajesh K. Kharbanda and Michael M. H. Cheung and Andrew N Redington},
  journal={Acta physiologica},
  year={2007},
  volume={190 2},
  pages={103-9}
}
AIM Intermittent limb ischaemia prior to cardiac ischaemia is a cardioprotective stimulus. This study was to investigate whether this peripheral stimulus had any effects on basal coronary blood flow and resistance, and to explore its potential mechanisms by studying the effect of femoral nerve transection and Katp blockade by glibenclamide. METHODS Remote ischaemic preconditioning (rIPC) was induced by four 5-min cycles of lower limb ischaemia. Coronary resistance was measured using standard… CONTINUE READING
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