Effects of intermittent administration of parathyroid hormone on bone augmentation in rat calvarium.

@article{Tsunori2015EffectsOI,
  title={Effects of intermittent administration of parathyroid hormone on bone augmentation in rat calvarium.},
  author={Katsuyoshi Tsunori and Shuichi Sato and Akira Hasuike and Soichiro Manaka and Hiromichi Shino and Nobuaki Sato and Tatsuya Kubota and Yoshinori Arai and Koichi Ito and Masashi Miyazaki},
  journal={Implant dentistry},
  year={2015},
  volume={24 2},
  pages={142-8}
}
OBJECTIVES This study examined the effects of parathyroid hormone (PTH) on bone augmentation beyond the skeletal envelope within a plastic cap in rat calvaria. MATERIALS AND METHODS The calvaria of 30 rats were exposed, and 2 plastic caps were placed on each. Each of the 10 rats was treated with 35 or 105 μg/kg (PTH-35, PTH-105) PTH 3 times per week. The control group was injected with sterile saline 3 times per week. Micro-computed tomography (CT) imaging was performed every 2 weeks for 12… CONTINUE READING
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