Effects of intermedin on dorsal root ganglia in the transmission of neuropathic pain in chronic constriction injury rats.

@article{Xiong2015EffectsOI,
  title={Effects of intermedin on dorsal root ganglia in the transmission of neuropathic pain in chronic constriction injury rats.},
  author={Wei Xiong and Shu-yi Qiu and Ling-yun Xu and Chun-ping Zhang and Yun Jae Yi and Qin Wu and Liping Huang and Shuang-mei Liu and B Wu and Li-chao Peng and Miao-miao Song and Yun Gao and Shang-dong Liang},
  journal={Clinical and experimental pharmacology & physiology},
  year={2015},
  volume={42 7},
  pages={780-7}
}
Neuropathic pain is a common and severely disabling state that affects millions of people worldwide. The P2X3 receptor plays a crucial role in facilitating pain transmission. Intermedin (IMD), which is also known as adrenomedullin 2 (AMD2) is a newly discovered hormone that is a member of the calcitonin/calcitonin gene-related peptide family. The present research investigates the effects of IMD on pain transmission in neuropathic pain states as mediated by P2X3 receptors in dorsal root ganglia… CONTINUE READING

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