Effects of interleukin-10 on cutaneous wounds and scars in humans of African continental ancestral origin.

@article{Kieran2014EffectsOI,
  title={Effects of interleukin-10 on cutaneous wounds and scars in humans of African continental ancestral origin.},
  author={Ingrid Kieran and Catherine Taylor and Jim Bush and Mark Rance and Karen So and Adam Boanas and Anthony Metcalfe and Rosalind Hobson and Nick Goldspink and John Hutchison and Mark Ferguson},
  journal={Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society},
  year={2014},
  volume={22 3},
  pages={326-33}
}
Scars in humans of African continental ancestry heal with an exaggerated inflammatory response and a generally wider scar. Interleukin-10 is an anti-inflammatory and antifibrotic cytokine. A randomized controlled trial in Caucasians found that exogenous interleukin-10 resulted in improved macroscopic scar appearance and reduced scar redness. We investigated the effects of interleukin-10 on cutaneous scarring in volunteers of African ancestral origin in an exploratory, single-center, within… CONTINUE READING

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A randomized controlled trial in Caucasians found that exogenous interleukin-10 resulted in improved macroscopic scar appearance and reduced scar redness .
A randomized controlled trial in Caucasians found that exogenous interleukin-10 resulted in improved macroscopic scar appearance and reduced scar redness .
A randomized controlled trial in Caucasians found that exogenous interleukin-10 resulted in improved macroscopic scar appearance and reduced scar redness .
A randomized controlled trial in Caucasians found that exogenous interleukin-10 resulted in improved macroscopic scar appearance and reduced scar redness .
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