Effects of interleukin-10 on activation and apoptosis of hepatic stellate cells in fibrotic rat liver.

@article{Zhang2006EffectsOI,
  title={Effects of interleukin-10 on activation and apoptosis of hepatic stellate cells in fibrotic rat liver.},
  author={Li-juan Zhang and Wei-da Zheng and Mei-Na Shi and Xiao-zhong Wang},
  journal={World journal of gastroenterology},
  year={2006},
  volume={12 12},
  pages={
          1918-23
        }
}
AIM To study the effects of interleukin-10 (IL-10) on the expression of alpha-smooth muscle actin (alpha-SMA), nuclear factor- kappa B(NF- kappa B) and Fas/Fas ligand (FasL) in hepatic stellate cells of experimental rats with hepatic fibrosis. METHODS Sixty clean SD rats were randomly divided into control group (group N), liver fibrotic group (group C) and IL-10 treatment group (group I). Control group received intraperitoneal injection of saline (2 mL/kg), twice a week. Fibrotic group was… CONTINUE READING

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