Effects of interleukin-1, -2, -4, -6, interferon-gamma and granulocyte/macrophage colony stimulating factor on human vascular endothelial cells.

@article{Holzinger1993EffectsOI,
  title={Effects of interleukin-1, -2, -4, -6, interferon-gamma and granulocyte/macrophage colony stimulating factor on human vascular endothelial cells.},
  author={Christoph Holzinger and Eva Maria Weissinger and Andreas Zuckermann and Martin Imhof and F Kink and A Sch{\"o}llhammer and Corinna Kopp and Ernst Wolner},
  journal={Immunology letters},
  year={1993},
  volume={35 2},
  pages={109-17}
}
Human vascular endothelial cells (HUVEC) exhibit various immunological functions, i.e. expression of HLA class-II antigens after incubation with IFN-gamma or antigen presenting function. It has also been reported that HUVEC are able to produce IL-1, IL-6, GM-CSF and immunologically active cleavage products of arachidonic acid. In our study we investigated whether various cytokines, namely IL-1, IL-2, IL-6, GM-CSF and IFN-gamma, do alter the proliferative capacity of HUVEC, the production of van… CONTINUE READING
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