Effects of interferon plus ribavirin treatment on NF-κB, TGF-β1, and metalloproteinase activity in chronic hepatitis C

@article{Guido2006EffectsOI,
  title={Effects of interferon plus ribavirin treatment on NF-κB, TGF-β1, and metalloproteinase activity in chronic hepatitis C},
  author={Maria Guido and Lucia de Franceschi and Nicola Olivari and Gioacchino Leandro and Martina Felder and Roberto Corrocher and M Rugge and Michela Pasino and Cristiano Lanza and Paola Capelli and Giovanna Fattovich},
  journal={Modern Pathology},
  year={2006},
  volume={19},
  pages={1047-1054}
}
Little is known about the cellular and molecular mechanisms underlying the effects of anti-viral therapy on the regression of liver inflammation and fibrosis in chronic hepatitis C. The aim of this study was to evaluate the effects of interferon alpha and ribavirin in combination therapy on the tissue expression of nuclear-factor kB (NF-κB) (a transcription factor coordinating the expression of stress genes involved in immune response and inflammation), of the polypeptide transforming growth… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 52 references

Divergent role of matrix metalloproteinase-2 in hepatic stellate cell activation and liver fibrosis

  • B Radbill, R Gupta, C. Alvarez
  • Hepatology
  • 2004

Effect of Peginterferon alpha - 2 a on liver histology in chronic hepatitis C : a meta - analysis of individual patients data

  • T Poynard, J McHutchison, GL Davis
  • Hepatology
  • 2004

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