Effects of inositol 1,2,6-triphosphate on human liver cancer SMMC-7721 cells

  title={Effects of inositol 1,2,6-triphosphate on human liver cancer SMMC-7721 cells},
  author={Yaming Zhou and Mou-cheng Wu and Hong Jiang},
  journal={Medicinal Chemistry Research},
Phytic acid (myo-inositol hexaphosphoric acid) is present substantially in plant kingdom, and has striking anticancer effects. Phytic acid can be hydrolyzed into lower inositol phosphates by partial dephosphorylation during food processing. Inositol 1,2,6-triphosphate [Ins(1,2,6)P3] is the derivative of phytic acid prepared by partial hydrolysis of phytic acid with Aspergillus terreus phytase. The effects of Ins(1,2,6)P3 on the cell proliferation rate, cell cycle distribution… 

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Med Chem Res
  • Med Chem Res
  • 2012