Effects of inhibitors of S-adenosylmethionine decarboxylase and ornithine decarboxylase on DNA synthesis in rat liver after partial hepatectomy.

@article{Wiegand1978EffectsOI,
  title={Effects of inhibitors of S-adenosylmethionine decarboxylase and ornithine decarboxylase on DNA synthesis in rat liver after partial hepatectomy.},
  author={Laurel Wiegand and Anthony E. Pegg},
  journal={Biochimica et biophysica acta},
  year={1978},
  volume={517 1},
  pages={169-80}
}
The effects of inhibitors of polyamine synthesis on DNA synthesis in rat liver regenerating after partial hepatectomy were studied. Neither 1,1'-[(methylethanediylidene)-dinitrilo]-bis-(3-aminoguanidine), a potent irreversible inhibitor of S-adenosylmethionine decarboxylase, nor 1,3-diaminopropane, an indirect inhibitor of ornithine decarboxylase, strongly… CONTINUE READING