Effects of infectious hematopoietic necrosis virus and infectious pancreatic necrosis virus infection on hematopoietic precursors of the zebrafish.

@article{Lapatra2000EffectsOI,
  title={Effects of infectious hematopoietic necrosis virus and infectious pancreatic necrosis virus infection on hematopoietic precursors of the zebrafish.},
  author={Scott E Lapatra and Linda Barone and Gareth R. Jones and Leonard I. Zon},
  journal={Blood cells, molecules & diseases},
  year={2000},
  volume={26 5},
  pages={
          445-52
        }
}
The zebrafish Danio rerio is a new model system for studying the genetics of hematopoiesis. To define naturally occurring viruses which could infect and replicate within hematopoietic precursors of the zebrafish, infectious hematopoietic necrosis virus (IHNV) and infectious pancreatic necrosis virus (IPNV) were studied. Infection of whole fish with viral supernatants demonstrated infectious replicants for both viruses, indicating that the virus host range includes the zebrafish. In other… CONTINUE READING
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