Effects of inducible glial fibrillary acidic protein on glioma cell motility and proliferation.

@article{Elobeid2000EffectsOI,
  title={Effects of inducible glial fibrillary acidic protein on glioma cell motility and proliferation.},
  author={Adila Elobeid and Erik Bongcam-Rudloff and Bengt Westermark and Monica Nist{\'e}r},
  journal={Journal of neuroscience research},
  year={2000},
  volume={60 2},
  pages={245-56}
}
We have studied the effect of induced glial fibrillary acidic protein (GFAP) on motility, cell morphology, and proliferation of two originally GFAP-negative human glioma cell lines. Glioma cell lines U-1242 MG and U-251 MG sp subclone 3A were transfected with a vector system that allows for an inducible GFAP expression. This experimental system creates an "on/off" situation in which GFAP expression is suppressed by tetracycline. Inducible expression of GFAP in the absence of tetracycline was… CONTINUE READING