Effects of indorenate on food intake: a comparison with fenfluramine and amphetamine

@article{Martnez2005EffectsOI,
  title={Effects of indorenate on food intake: a comparison with fenfluramine and amphetamine},
  author={D. N. Vel{\'a}zquez Mart{\'i}nez and M. Valencia Flores and M. L{\'o}pez Cabrera and J. Villarreal},
  journal={Psychopharmacology},
  year={2005},
  volume={117},
  pages={91-101}
}
Indorenate (TR3369, 5-methoxytryptamine b-methylcarboxylate HCl) is a 5-HT1-like receptor agonist with hypotensive activity. Here, we describe that indorenate also decreases food intake (ED50 26.1 mg/kg) without an appreciable effect in water intake (the estimated ED50 for water was 589.8 mg/kg). The anorectic activity of indorenate was compared to the effects of amphetamine and other serotonin agonists; the effect of indorenate was smaller than those of the other compounds; however, the effect… Expand
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