Effects of indomethacin on kidney function in Type 1 (insulin-dependent) diabetic patients with nephropathy


We investigated whether the glomerular synthesis of prostaglandins modulates the glomerular filtration rate and albumimiria in diabetic nephropathy. The urinary excretion of immunoreactive prostaglandin E2 (253pg/min) was significantly elevated in eight Type 1 (insulin-dependent) diabetic women with nephropathy as compared with nine normoalbuminuric Type 1… (More)
DOI: 10.1007/BF00274575


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