Effects of indomethacin on ICAM-1 expression and adhesion of T lymphocytes to chondrocytes

It is now recognized that indomethacin, a frequently prescribed non-steroidal anti-inflammatory drug, may itself exert detrimental effects on cartilage matrix metabolism. In this study, the effects of indomethacin on one aspect of chondrocyte behaviour have been investigated. Using standard indirect immunolocalization techniques, it was demonstrated that… CONTINUE READING