Effects of imidazolines on neurogenic contraction in isolated urinary bladder detrusor strips from rabbit.

@article{He2012EffectsOI,
  title={Effects of imidazolines on neurogenic contraction in isolated urinary bladder detrusor strips from rabbit.},
  author={Hong-mei He and Lei-ming Ren and He-lin Tian and Hai-gang Lu and Ding Zhao},
  journal={Canadian journal of physiology and pharmacology},
  year={2012},
  volume={90 2},
  pages={
          219-27
        }
}
  • Hong-mei He, L. Ren, Ding Zhao
  • Published 6 February 2012
  • Biology, Chemistry, Medicine
  • Canadian journal of physiology and pharmacology
Moxonidine and clonidine, which are imidazoline compounds, are sympathetic modulators used as centrally acting antihypertensive drugs. Moxonidine, clonidine, and agmatine produce extensive effects in mammalian tissues via imidazoline recognition sites (or receptors) or α(2)-adrenoceptors. To investigate the effects of imidazolines on the function of the urinary bladder, we tested the effects of moxonidine, clonidine, and agmatine on the neurogenic contraction induced by electric field… 
3 Citations
Urinary Bladder Relaxation through Activation of Imidazoline Receptors Induced by Agmatine is Increased in Diabetic Rats
TLDR
The effect of agmatine on bladder contractility and the diabetes‐induced alteration of this action were studied in the rat and the results confirmed the importance of knowing the carrier and removal status of this substance in the menstrual cycle.

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