Effects of imidazoline receptor ligands on monoamine synthesis in the rat brain in vivo

@article{SastreColl1999EffectsOI,
  title={Effects of imidazoline receptor ligands on monoamine synthesis in the rat brain in vivo},
  author={A. Sastre-Coll and S. Esteban and J. Garc{\'i}a-Sevilla},
  journal={Naunyn-Schmiedeberg's Archives of Pharmacology},
  year={1999},
  volume={360},
  pages={50-62}
}
Abstract This study was designed to assess the effects of imidazoline drugs on putative presynaptic imidazoline receptors modulating brain monoamine synthesis in vivo. The accumulation of 3,4-dihydroxyphenylalanine (dopa) and 5-hydroxytryptophan (5-HTP) after decarboxylase inhibition was used as a measure of the rate of tyrosine and tryptophan hydroxylation in various brain regions of naive rats and after irreversible α2-adrenoceptor inactivation with EEDQ (1.6 mg/kg, i.p., 6 h).Clonidine (1–3… Expand
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References

SHOWING 1-10 OF 35 REFERENCES
Serotonin 5-HT1A receptors mediate inhibition of tyrosine hydroxylation in rat striatum.
...
1
2
3
4
...