Effects of imidapril on heterogeneity of action potential and calcium current of ventricular myocytes in infarcted rabbits.


AIM To investigate the effects of chronic treatment with imidapril on the electrophysiologic heterogeneous change of the noninfarcted myocardium of rabbits after myocardial infarction and the mechanism of its antiarrhythmic efficacy. METHODS Rabbits with left coronary artery ligation were prepared and allowed to recover for 8 weeks. Myocytes were isolated… (More)