Effects of iRoot BP and white mineral trioxide aggregate on cell viability and the expression of genes associated with mineralization.

@article{Torun2015EffectsOI,
  title={Effects of iRoot BP and white mineral trioxide aggregate on cell viability and the expression of genes associated with mineralization.},
  author={Zeynep {\"O}ncel Torun and Deniz Torun and Kadriye Demirkaya and S{\"u}leyman Tolga Yavuz and Mualla Pınar Elçi and Meral Sarper and Ferit Avcu},
  journal={International endodontic journal},
  year={2015},
  volume={48 10},
  pages={986-93}
}
AIM To evaluate the cytotoxicity and mineralization effects of iRoot BP in human dental pulp cells (hDPCs) and to compare them with those of white mineral trioxide aggregate (WMTA). METHODOLOGY hDPCs were exposed to prepared dilutions (1 : 1-1 : 10) of the test materials. Cell viability was evaluated using the XTT assay after incubation periods of 24, 48 or 72 h. The expression of mineralization-related genes (bone morphogenic protein, osteonectin, bone sialoprotein, osteopontin, dentine… CONTINUE READING