Effects of hypoxia on human cancer cell line chemosensitivity

@inproceedings{Strese2013EffectsOH,
  title={Effects of hypoxia on human cancer cell line chemosensitivity},
  author={Sara Strese and M{\aa}rten Frykn{\"a}s and Rolf Larsson and Joachim Gullbo},
  booktitle={BMC Cancer},
  year={2013}
}
BackgroundEnvironment inside even a small tumor is characterized by total (anoxia) or partial oxygen deprivation, (hypoxia). It has been shown that radiotherapy and some conventional chemotherapies may be less effective in hypoxia, and therefore it is important to investigate how different drugs act in different microenvironments. In this study we perform a large screening of the effects of 19 clinically used or experimental chemotherapeutic drugs on five different cell lines in conditions of… CONTINUE READING

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