Effects of hypoxia and nitric oxide on ferritin content of alveolar cells.

@article{Smith2003EffectsOH,
  title={Effects of hypoxia and nitric oxide on ferritin content of alveolar cells.},
  author={Jacqueline J. Smith and Amy R O'Brien-Ladner and Chris R Kaiser and Lewis J. Wesselius},
  journal={The Journal of laboratory and clinical medicine},
  year={2003},
  volume={141 5},
  pages={
          309-17
        }
}
Concentrations of ferritin in alveolar cells and on the alveolar surface are increased in patients with a variety of respiratory disorders. Ferritin synthesis by cells is modulated by iron content but is also influenced by stimuli other than iron. In this study we sought to determine whether in vitro exposure to hypoxia- or nitric oxide (NO)-induced ferritin accumulation or release by human alveolar macrophages (AMs) or a lung cancer-derived epithelial cell line (A549). Changes in cell content… CONTINUE READING

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