Effects of hypoxia and hypercapnia on surfactant protein expression proliferation and apoptosis in A549 alveolar epithelial cells.

@article{Vaporidi2005EffectsOH,
  title={Effects of hypoxia and hypercapnia on surfactant protein expression proliferation and apoptosis in A549 alveolar epithelial cells.},
  author={Katerina Vaporidi and Christos Tsatsanis and Dimitris Georgopoulos and Philip N Tsichlis},
  journal={Life sciences},
  year={2005},
  volume={78 3},
  pages={284-93}
}
UNLABELLED During lung injury alveolar epithelial cells are directly exposed to changes in PO(2) and PCO(2). Integrity of alveolar epithelial type II cells (AECII) is critical in lung injury but the effect of hypoxia and hypercapnia on AECII function, viability and proliferation has not been clearly investigated. Aim of the present work was to determine the direct effect of hypoxia and hypercapnia on surfactant protein expression, proliferation and apoptosis of lung epithelial cells in vitro… CONTINUE READING

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