Effects of hypothyroidism on the estrous cycle and reproductive hormones in mature female rat.

@article{Hatsuta2004EffectsOH,
  title={Effects of hypothyroidism on the estrous cycle and reproductive hormones in mature female rat.},
  author={Minoru Hatsuta and Keiko Abe and Kazuhiro Tamura and Takamitsu Ryuno and Gen Watanabe and Kazuyoshi Taya and Hiroshi Kogo},
  journal={European journal of pharmacology},
  year={2004},
  volume={486 3},
  pages={343-8}
}
The present study was undertaken to examine the systemic role of thyroid hormones by analyzing changes in reproductive functions in hypothyroid female rats. Serum concentrations of triiodo-thyronine (T3) significantly decreased 1 week after the initiation of propyl-thiouracil treatment or thyroidectomy. The estrous cycle became irregular 3 and 2 weeks after the initiation of propyl-thiouracil treatment and thyroidectomy, respectively. Serum luteinizing hormone (LH) levels significantly reduced… CONTINUE READING
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