Effects of hypoperfusion in Alzheimer's disease.

  title={Effects of hypoperfusion in Alzheimer's disease.},
  author={Benjamin Piya Austin and Veena A. Nair and Timothy B. Meier and Guofan Xu and Howard A. Rowley and Cynthia M Carlsson and Sterling C. Johnson and Vivek Prabhakaran},
  journal={Journal of Alzheimer's disease : JAD},
  volume={26 Suppl 3},
The role of hypoperfusion in Alzheimer's disease (AD) is a vital component to understanding the pathogenesis of this disease. Disrupted perfusion is not only evident throughout disease manifestation, it is also demonstrated during the pre-clinical phase of AD (i.e., mild cognitive impairment) as well as in cognitively healthy persons at high-risk for developing AD due to family history or genetic factors. Studies have used a variety of imaging modalities (e.g., SPECT, MRI, PET) to investigate… 

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