Effects of hypohydration on lung functions in humans.

  title={Effects of hypohydration on lung functions in humans.},
  author={Shahrokh Javaheri and C H Bosken and Seung Pyung Lim and Michael N. Dohn and Nancy Greene and Robert P Baughman},
  journal={The American review of respiratory disease},
  volume={135 3},
We studied lung function tests during euhydration (Days 1 and 2), hypohydration (Days 3 and 4), and rehydration (Days 5, 6, and 7) in 6 normal subjects. Hypohydration was induced by administering chlorthalidone, and this resulted in a 4.5% loss of body weight. During hypohydration, lung volumes increased significantly. Interestingly, ventilatory lung function tests including peak expiratory flow rate, FEV1, maximal voluntary ventilation, and flow rates at low lung volumes also increased… CONTINUE READING


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