Effects of hypertonic solution on action potential and input resistance in the guinea-pig ventricular muscle.

@article{Ehara1983EffectsOH,
  title={Effects of hypertonic solution on action potential and input resistance in the guinea-pig ventricular muscle.},
  author={Tsuguhisa Ehara and J. Hasegawa},
  journal={The Japanese journal of physiology},
  year={1983},
  volume={33 2},
  pages={151-67}
}
The effects of hypertonic solution on action potential and input resistance were studied using the guinea-pig ventricular muscle. Hypertonic solutions containing excess (150 and 300 mOsm/liter) sucrose, glucose, NaCl, Na2SO4, or LiCl produced a prolongation of action potential duration (APD) followed by a gradual shortening. These solutions increased the input resistance of the preparation. The prolongation of APD began immediately after the onset of perfusion with hypertonic solution and… CONTINUE READING
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Dual effect of hypertonic solution on the action potential

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