Effects of hypertonic saline on expression of human polymorphonuclear leukocyte adhesion molecules.


Hypertonic saline prevents vascular adherence of neutrophils and ameliorates ischemic tissue injury. We hypothesized that hypertonic saline attenuates N-formyl-methionyl-leucyl-phenylalanine (fMLP)-stimulated expression of adhesion molecules on human polymorphonuclear leukocytes (PMNLs). fMLP-stimulated up-regulation of beta2-integrins was diminished by… (More)

15 Figures and Tables


  • Presentations referencing similar topics