Effects of hyperthermia on contraction and dilatation of rabbit femoral arteries.

@article{Padilla1998EffectsOH,
  title={Effects of hyperthermia on contraction and dilatation of rabbit femoral arteries.},
  author={Jes{\'u}s Padilla and {\'A}ngel Luis Garc{\'i}a-Villal{\'o}n and Nuria Montero Fern{\'a}ndez and Luis Monge and Bernardino G{\'o}mez and Godofredo Di{\'e}guez},
  journal={Journal of applied physiology},
  year={1998},
  volume={85 6},
  pages={2205-12}
}
To analyze the effect of hyperthermia on the vascular response, the isometric response of isolated rabbit femoral artery segments was recorded at 37 degreesC and hyperthermia (41 and 44 degreesC). Contraction to potassium (5 x 10(-3)-5 x 10(-2) M) was significantly greater at 41 and 44 than at 37 degreesC and increased by inhibition of nitric oxide (NO) synthesis with Nomega-nitro-L-arginine (L-NNA; 10(-4) M) or endothelium removal at 37 degreesC but not at 41 or 44 degreesC. Norepinephrine (10… CONTINUE READING

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