Effects of hyperinsulinemia and obesity on risk of neural tube defects among Mexican Americans.

@article{Hendricks2001EffectsOH,
  title={Effects of hyperinsulinemia and obesity on risk of neural tube defects among Mexican Americans.},
  author={Katherine A. Hendricks and O M Nuno and Lucina Suarez and Russell Larsen},
  journal={Epidemiology},
  year={2001},
  volume={12 6},
  pages={630-5}
}
Although both maternal obesity and diabetes mellitus increase the risk for neural tube defects, it is unknown whether they are independent risk factors or manifestations of an underlying prediabetic state such as hyperinsulinemia. We investigated whether hyperinsulinemia was a risk factor for neural tube defects independent of obesity and hyperglycemia in Mexican-American women. We identified case and control women from residents delivering or terminating pregnancies in hospitals or birthing… CONTINUE READING

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