Effects of hyperbaric oxygen therapy on cerebral oxygenation and mitochondrial function following moderate lateral fluid-percussion injury in rats.

@article{Daugherty2004EffectsOH,
  title={Effects of hyperbaric oxygen therapy on cerebral oxygenation and mitochondrial function following moderate lateral fluid-percussion injury in rats.},
  author={Wilson P. Daugherty and Joseph E Levasseur and Dong Sun and Gaylan L. Rockswold and Malcolm Ross Bullock},
  journal={Journal of neurosurgery},
  year={2004},
  volume={101 3},
  pages={499-504}
}
OBJECT In the current study, the authors examined the effects of hyperbaric O2 (HBO) following fluid-percussion brain injury and its implications on brain tissue oxygenation (PO2) and O2 consumption (VO2) and mitochondrial function (redox potential). METHODS Cerebral tissue PO2 was measured following induction of a lateral fluid-percussion brain injury in rats. Hyperbaric O2 treatment (100% O2 at 1.5 ata) significantly increased brain tissue PO2 in both injured and sham-injured animals. For… CONTINUE READING