Effects of hydroxypropyl cyclodextrins on the reactivation of SDS-denatured aminoacylase.

Abstract

Cyclodextrins are natural-occurring circular oligosaccharides with an internal hydrophobic cavity and external hydrophilic edges. Because cyclodextrins bind with protein aromatic residues, they can prevent protein aggregation, and their ability to bind with detergents enables them to act as stripping reagents to release proteins from protein-detergent… (More)

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