Effects of hydroxyethylstarch and gelatin on renal function in severe sepsis: a multicentre randomised study.

@article{Schortgen2001EffectsOH,
  title={Effects of hydroxyethylstarch and gelatin on renal function in severe sepsis: a multicentre randomised study.},
  author={Fr{\'e}d{\'e}rique Schortgen and Jean Claude Lacherade and Fabrice Bruneel and Isabelle Cattaneo and François Hemery and François Lemaire and L. Brochard},
  journal={Lancet},
  year={2001},
  volume={357 9260},
  pages={911-6}
}
BACKGROUND Hydroxyethylstarch used for volume restoration in brain-dead kidney donors has been associated with impaired kidney function in the transplant recipients. We undertook a multicentre randomised study to assess the frequency of acute renal failure (ARF) in patients with severe sepsis or septic shock treated with hydroxyethylstarch or gelatin. METHODS Adults with severe sepsis or septic shock were enrolled prospectively in three intensive-care units in France. They were randomly… CONTINUE READING
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