Effects of human trophoblast-induced interferons on the expression of proto-oncogenes c-fms/CSF-1R, EGF-R and c-erbB2 in invasive and non-invasive trophoblast.

@article{AboagyeMathiesen1997EffectsOH,
  title={Effects of human trophoblast-induced interferons on the expression of proto-oncogenes c-fms/CSF-1R, EGF-R and c-erbB2 in invasive and non-invasive trophoblast.},
  author={G. Aboagye-Mathiesen and Maja Zdravkovic and Ferenc D. T{\'o}th and Peter Ebbesen},
  journal={Placenta},
  year={1997},
  volume={18 2-3},
  pages={155-61}
}
The human cytotrophoblast is the first fetal cell type to arise during embryogenesis and differentiate along two pathways to the invasive (extravillous) and non-invasive (villous) populations. The non-invasive villous trophoblast differentiate morphologically and biochemically to form terminally differentiated multinucleated syncytial trophoblast. First trimester invasive and non-invasive trophoblast were isolated from human placentae (5-12 weeks) and were cultured in vitro. The villous… CONTINUE READING