Effects of hormone-replacement therapy on fibrinolysis in postmenopausal women.

@article{Koh1997EffectsOH,
  title={Effects of hormone-replacement therapy on fibrinolysis in postmenopausal women.},
  author={Kwang Kon Koh and R M Mincemoyer and Minh N Bui and Gyorgy Csako and Frank Pucino and V Guetta and Myron A. Waclawiw and Richard O. Cannon},
  journal={The New England journal of medicine},
  year={1997},
  volume={336 10},
  pages={683-90}
}
BACKGROUND Plasma levels of plasminogen-activator inhibitor type 1 (PAI-1), an essential inhibitor of fibrinolysis in humans, increase in women after menopause, and this may contribute to the risk of cardiovascular disease. We studied the effects of hormone-replacement therapy on PAI-1 levels. METHODS In a randomized, crossover study, we investigated the effects of oral conjugated estrogen (0.625 mg per day) in 30 postmenopausal women and transdermal estradiol (0.1 mg per day) in 20… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 106 extracted citations

Similar Papers

Loading similar papers…