Effects of hormone replacement therapy and antioxidant vitamin supplements on coronary atherosclerosis in postmenopausal women: a randomized controlled trial.

@article{Waters2002EffectsOH,
  title={Effects of hormone replacement therapy and antioxidant vitamin supplements on coronary atherosclerosis in postmenopausal women: a randomized controlled trial.},
  author={David D Waters and Edwin L. Alderman and Judith Hsia and Barbara V Howard and Frederick R. Cobb and William J. Rogers and Pamela Ouyang and Paul Thompson and Jean Claude Tardif and Lyall A. J. Higginson and V Garrett Bittner and Michael W. Steffes and David J. Gordon and Michael A Proschan and Naji Younes and Joel I Verter},
  journal={JAMA},
  year={2002},
  volume={288 19},
  pages={2432-40}
}
CONTEXT Hormone replacement therapy (HRT) and antioxidant vitamins are widely used for secondary prevention in postmenopausal women with coronary disease, but no clinical trials have demonstrated benefit to support their use. OBJECTIVE To determine whether HRT or antioxidant vitamin supplements, alone or in combination, influence the progression of coronary artery disease in postmenopausal women, as measured by serial quantitative coronary angiography. DESIGN, SETTING, AND PATIENTS The… CONTINUE READING

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