Effects of hormone replacement therapy and high-impact physical exercise on skeletal muscle in post-menopausal women: a randomized placebo-controlled study.

@article{Sipil2001EffectsOH,
  title={Effects of hormone replacement therapy and high-impact physical exercise on skeletal muscle in post-menopausal women: a randomized placebo-controlled study.},
  author={Sarianna Sipil{\"a} and Dennis R Taaffe and Sulin Cheng and Jukka Puolakka and Jarmo Toivanen and Harri Suominen},
  journal={Clinical science},
  year={2001},
  volume={101 2},
  pages={147-57}
}
An age-related decline in muscle performance is a known risk factor for falling, fracture and disability. In women, a clear deterioration is observed from early menopause. The effect of hormone replacement therapy (HRT) in preserving muscle performance is, however, unclear. This trial examined the effects of a 12-month HRT and high-impact physical exercise regimen on skeletal muscle in women in early menopause. A total of 80 women aged 50-57 years were assigned randomly to one of four groups… CONTINUE READING
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