Effects of histidine and imidazolelactic acid on various parameters of the oxidative stress in cerebral cortex of young rats.


Histidinemia is an inherited metabolic disorder caused by deficiency of histidase activity, which leads to tissue accumulation of histidine and its derivatives. Affected patients usually present with speech delay and mental retardation, although asymptomatic patients have been reported. Considering that the pathophysiology of the neurological dysfunction of… (More)


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