Effects of hirsutine and dihydrocorynantheine on the action potentials of sino-atrial node, atrium and ventricle.

Abstract

The effects of hirsutine, an indole alkaloid from Uncaria rhynchophylla MIQ. JACKSON with antihypertensive, negative chronotropic and antiarrhythmic activity, and its C3 structural epimer, dihydrocorynantheine, on membrane potentials of rabbit sino-atrial node and guinea-pig right ventricle and left atrium were studied with microelectrode techniques. In… (More)

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Cite this paper

@article{Masumiya1999EffectsOH, title={Effects of hirsutine and dihydrocorynantheine on the action potentials of sino-atrial node, atrium and ventricle.}, author={Haruko Masumiya and T.. Saitoh and Y. Tanaka and Shigeo Horie and Noriro Aimi and Hisashi Takayama and H. Tanaka and Keiichi Shigenobu}, journal={Life sciences}, year={1999}, volume={65 22}, pages={2333-41} }