Effects of hippocampal lesioning on experimental periodontitis in Wistar rats.

@article{Breivik2002EffectsOH,
  title={Effects of hippocampal lesioning on experimental periodontitis in Wistar rats.},
  author={Torbj\orn Breivik and Per Stanley Thrane and Per E. Gjermo and A. A. Cools and Trond Myhrer},
  journal={Journal of periodontal research},
  year={2002},
  volume={37 5},
  pages={360-5}
}
The hippocampus, which is a brain structure involved in learning and memory processes, plays a key role in the feedback regulation of the hypothalamic-pituitary-adrenal (HPA) axis and autonomic sympathetic nervous system, and the subsequent secretion of immuno-modulatory hormones in response to pathogenic microorganisms. Dysregulation of these brain-neuroendocrine-immune regulatory networks, which act in concert to maintain homeostasis, is found to be of critical importance to the host defence… CONTINUE READING