Effects of hexachlorophene on the metabolism of glucose and glutamate in rat brain.
@article{DeLucia1978EffectsOH, title={Effects of hexachlorophene on the metabolism of glucose and glutamate in rat brain.}, author={Raffaele De Lucia and Luis O. Medeiros and L. F. Medeiros and Moacyr Luiz Aizenstein and L B Valle and Ricardo M. Oliveira-filho}, journal={General pharmacology}, year={1978}, volume={9 5}, pages={ 321-4 } }
5 Citations
In vitro kinetics of the rat brain succinate dehydrogenase inhibition by hexachlorophene
- Chemistry, BiologyJournal of biochemical and molecular toxicology
- 1999
Brain succinate dehydrogenase (SDH) activity was inhibited by in vitro hexachlorophene (HCP) with a half inhibitory concentration (IC50) of 0.65 × 10−3 M; the brain SDH demands more energy of activation (ΔE) in the presence of HCP.
Patterns of mid-to-term placental enzymes in rats treated with magnesium sulphate.
- Biology, ChemistryGeneral pharmacology
- 1982
In vitro kinetics of the mouse hepatic arginase inhibition by hexachlorophene
- Biology, Chemistry
- 1987
Inhibition of sheep brain acetylcholinesterase by hexachlorophene
- BiologyBulletin of environmental contamination and toxicology
- 1987
An attempt has been made to assess the response of acetylcholinesterase (ACHE) to HCP treatment in vitro, and it is possible that neurotransmission could also be affected.
Effects of chlorinated bisphenols on torula yeast glucose-6-phosphate dehydrogenase.
- Chemistry, BiologyJournal of toxicology and environmental health
- 1981
Chlorinated bisphenol antibacterial and antifungal agents are potent inhibitors of torula yeast glucose-6-phosphate dehydrogenase (G6PD). Several compounds were tested, including hexachlorophene…
References
SHOWING 1-10 OF 29 REFERENCES
The effect of hexachlorophene on the respiration of brain and liver mitochondria.
- Biology, ChemistryBiochemical and biophysical research communications
- 1972
THE EFFECTS OF INTOXICATING DOSES OF ETHANOL UPON INTERMEDIARY METABOLISM IN RAT BRAIN
- Medicine, ChemistryJournal of neurochemistry
- 1972
It is suggested that the different effects observed in brain and liver result from the action of ethanol upon the nerve cell membrane in brain, whereas the primary target in liver is alcohol dehydrogenase.
Increase in cerebral fluids in rats after treatment with hexachlorophane or triethyltin.
- Chemistry, MedicineBiochemical pharmacology
- 1976
Effect of ehxachlorophene on hepatic drug-metabolizing enzymes in the rat.
- Biology, ChemistryBiochemical pharmacology
- 1974
Biochemical lesion in rat liver mitochondria induced by hexachlorophene.
- Biology, ChemistryBiochemical pharmacology
- 1972
THE GLUCOSE CONTENT OF BRAIN IN ANAESTHESIA *
- Biology, MedicineJournal of neurochemistry
- 1964
The discovery of an elevated ratio of brain glucose to serum glucose in phenobarbitonetreated mice suggested to us that the transport or the metabolism of glucose in the anaesthetized brain may be altered in a way not previously recognized.
Some neurochemical correlates of convulsive activity in the rat brain.
- Chemistry, BiologyBiochemical pharmacology
- 1972
Hexachlorophene effects on the rat brain: study of high doses by light and electron microscopy.
- BiologyArchives of environmental health
- 1971
Hexachlorophene was fed to female adult Sherman strain rats at 500 ppm (25 mg/kg/day) for 14 and 10 weeks in two consecutive studies; the rats regained almost complete recovery of leg function within six weeks.
The concentration of glucose in rat tissues.
- Biology, ChemistryThe Biochemical journal
- 1956
Both the diester and the (x)mono-ethyl ester of amino-oxoadipic acid have been shown to give rise to porphobilinogen or porphyrins in biological systems, but this is not, however, sufficient evidence to establish that amino- oxoadIPic acid is the biological precursor of aminolaevulic acid.
Factors affecting the glucose 6-phosphate inhibition of hexokinase from cerebral cortex tissue of the guinea pig.
- Biology, ChemistryThe Biochemical journal
- 1968
It is concluded that ATP potentiates glucose 6-phosphate inhibition of cerebral-cortex hexokinase, whereas the ATP-Mg(2+) complex has no effect and the physiological significance of the ATP, inorganic phosphate and alpha-glycerophosphate effects is discussed.