Effects of hetastarch and albumin on coagulation in patients with septic shock.

@article{Falk1988EffectsOH,
  title={Effects of hetastarch and albumin on coagulation in patients with septic shock.},
  author={Jay L. Falk and Eric C. Rackow and Mark Elton Astiz and Max Harry Weil},
  journal={Journal of clinical pharmacology},
  year={1988},
  volume={28 5},
  pages={412-5}
}
The effect of 6% hydroxyethyl starch (hetastarch) and 5% human serum albumin (albumin) infusion on coagulation in 12 patients with septic shock was evaluated. Patients were randomly assigned to receive either albumin (N = 6) or hetastarch (N = 6) infusion over a 24-hour study interval. The prothrombin time (PT), partial thromboplastin time (PTT), and quantitative platelet count (PC) were obtained prior to and following 24 hours of fluid infusion. Hetastarch patients received 4934 +/- 1354 mL… CONTINUE READING