Effects of herbal supplements on drug glucuronidation. Review of clinical, animal, and in vitro studies.

@article{Mohamed2011EffectsOH,
  title={Effects of herbal supplements on drug glucuronidation. Review of clinical, animal, and in vitro studies.},
  author={Mohamed-Eslam F Mohamed and R F Frye},
  journal={Planta medica},
  year={2011},
  volume={77 4},
  pages={311-21}
}
The use of herbal supplements has increased steadily over the last decade. Recent surveys show that many people who take herbal supplements also take prescription and nonprescription drugs, increasing the risk for potential herb-drug interactions. While cytochrome P450-mediated herb-drug interactions have been extensively characterized, the effects of herbal extracts and constituents on UDP-glucuronosyl transferase (UGT) enzymes have not been adequately studied. Thus, the purpose of this review… CONTINUE READING

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