Effects of heptaminol AMP amidate on suppressor and helper function of murine T cells.

@article{Saha1988EffectsOH,
  title={Effects of heptaminol AMP amidate on suppressor and helper function of murine T cells.},
  author={A. Saha and K. Ueno and S. Ohmori and T. Igarashi and H. Kitagawa},
  journal={Japanese journal of pharmacology},
  year={1988},
  volume={48 4},
  pages={
          417-22
        }
}
Heptaminol AMP amidate (HAA), a newly developed nucleotide derivative, was found to restore the immunosuppression in mice due to the induction of suppressor T (Ts) cells by concanavalin A (Con A) (50 micrograms/body). HAA also inhibited Con A-mediated in vitro induction of Ts cells. On the contrary, the administration of HAA in mice primed with keyhole lympet hemocyanin (KLH) (30 micrograms/body) caused an enhanced induction of antigen specific helper T (Th) cells. Effects of HAA on Ts and Th… Expand
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