Effects of heavy in utero cocaine exposure on adolescent caudate morphology.

  title={Effects of heavy in utero cocaine exposure on adolescent caudate morphology.},
  author={Brian B. Avants and Hallam Hurt and Joan M. Giannetta and Charles L. Epstein and David Shera and Hengyi Rao and Jiongjiong Wang and James C. Gee},
  journal={Pediatric neurology},
  volume={37 4},
We assess the effects of in utero cocaine and polysubstance exposure on the adolescent caudate nucleus through high-resolution magnetic resonance imaging. Cocaine exposure may compromise the developing brain through disruption of neural ontogeny in dopaminergic systems, effects secondary to fetal hypoxemia, or altered cerebrovascular reactivity. Cocaine exposure may also lead to neonatal lesions in the caudate. However, long-term or latent effects of intrauterine cocaine exposure are rarely… CONTINUE READING

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