Effects of heart rate on extracellular [K+] accumulation during myocardial ischemia.

@article{Weiss1986EffectsOH,
  title={Effects of heart rate on extracellular [K+] accumulation during myocardial ischemia.},
  author={Jonathan J. Weiss and Kenneth I Shine},
  journal={The American journal of physiology},
  year={1986},
  volume={250 6 Pt 2},
  pages={H982-91}
}
The effect of heart rate on extracellular [K+] ([K+]o) accumulation during total global ischemia was investigated in the isolated arterially perfused (37 degrees C) rabbit interventricular septum using intramyocardial K+-sensitive electrodes (tip diameter, 0.3 mm) and intracellular microelectrodes. The heart rates tested were 0, 25, 75, 125, and 150 beats/min in aqueous-perfused septa and 25, 75, and 125 beats/min in blood-perfused septa. In the lower range of heart rates (0-75 beats/min) the… CONTINUE READING

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