Effects of halothane on respiratory mechanics and lung histopathology in normal rats.

@article{Reta2000EffectsOH,
  title={Effects of halothane on respiratory mechanics and lung histopathology in normal rats.},
  author={G S Reta and Janeth Riva and H{\'e}ctor P{\'i}riz and Alessandra Medeiros and Patricia R M Rocco and Walter Ara{\'u}jo Zin},
  journal={British journal of anaesthesia},
  year={2000},
  volume={84 3},
  pages={372-7}
}
It is generally accepted that halothane reduces airway and tissue resistance in lungs with preexisting airway tone. However, under conditions of resting airway tone, pulmonary resistance remains unaltered. In this study, we have determined the effects of halothane on respiratory system, pulmonary and chest wall resistive, elastic and viscoelastic mechanical properties, and related the results to findings from lung histology in intact normal rats. Sixteen adult male Wistar rats were allocated… CONTINUE READING

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