Effects of haloperidol and amisulpride on motor and cognitive skill learning in healthy volunteers

@article{Peretti1997EffectsOH,
  title={Effects of haloperidol and amisulpride on motor and cognitive skill learning in healthy volunteers},
  author={Charles Siegfried Peretti and J. M. Danion and Françoise Kauffmann-Muller and Danielle Grang{\'e} and Alain A. Patat and Pierre Rosenzweig},
  journal={Psychopharmacology},
  year={1997},
  volume={131},
  pages={329-338}
}
The effects of a typical neuroleptic, haloperidol (1 and 2 mg orally), of an atypical neuroleptic, amisulpride (50 and 100 mg) and of a placebo on motor and cognitive skill learning were assessed in 60 healthy volunteers using repeated testing on the Tower of Toronto puzzle. Subjects were asked to solve three blocks of eight trials and, at distance from drug administration, a fourth block. The puzzle was connected to a computer in order to obtain a precise timing of individual moves. Two… CONTINUE READING

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