Effects of growth rate and promoter activity on single-cell protein expression

@inproceedings{Nordholt2017EffectsOG,
  title={Effects of growth rate and promoter activity on single-cell protein expression},
  author={Niclas Nordholt and Johan H. van Heerden and Remco Kort and Frank J. Bruggeman},
  booktitle={Scientific Reports},
  year={2017}
}
Protein expression in a single cell depends on its global physiological state. Moreover, genetically-identical cells exhibit variability (noise) in protein expression, arising from the stochastic nature of biochemical processes, cell growth and division. While it is well understood how cellular growth rate influences mean protein expression, little is known… CONTINUE READING