Effects of growth hormone in patients with tibial fracture: a randomised, double-blind, placebo-controlled clinical trial.

@article{Raschke2007EffectsOG,
  title={Effects of growth hormone in patients with tibial fracture: a randomised, double-blind, placebo-controlled clinical trial.},
  author={Michael Johannes Raschke and Michael H{\o}jby Rasmussen and Shunmugam Govender and David Segal and Mette Suntum and Jens Sandahl Christiansen},
  journal={European journal of endocrinology},
  year={2007},
  volume={156 3},
  pages={
          341-51
        }
}
OBJECTIVE Investigate whether intervention with GH after tibial fracture enhances fracture healing. DESIGN Randomised, double-blind, placebo-controlled study in 406 patients (93 women, 313 men, age: 18-64 years) with tibial fracture. METHODS Patients were stratified by tibial fracture (open or closed) and allocated to placebo or GH treatment (15, 30 or 60 mug/kg daily, until clinically assessed healing or until 16 weeks post-surgery). Primary outcome was time from surgery until fracture… CONTINUE READING
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