Effects of green pit viper (Trimeresurus erythrurus and Trimeresurus popeorum) venoms on blood coagulation, platelets and the fibrinolytic enzyme systems: studies in vivo and in vitro.

  title={Effects of green pit viper (Trimeresurus erythrurus and Trimeresurus popeorum) venoms on blood coagulation, platelets and the fibrinolytic enzyme systems: studies in vivo and in vitro.},
  author={Chulee Mitrakul},
  journal={American journal of clinical pathology},
  volume={60 5},
  • C. Mitrakul
  • Published 1 November 1973
  • Medicine
  • American journal of clinical pathology
The hemostatic disturbance caused by venoms of green pit vipers, the poisonous snakes commonly found in Bangkok, was studied in vivo and in vitro . The venoms were shown to possess: (1) clotting activity by thrombin-like action, direct on fibrinogen; this action was, however, not interfered with by heparin; (2) fibrinolytic activity by activating the activator system; (3) a direct aggregating effect on platelets. in vivo , the patients’ conditions usually returned to normal within a few weeks… Expand
The effects of green pit viper (Trimeresurus albolabris and Trimeresurus macrops) venom on the fibrinolytic system in human.
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Arboreal green pit vipers (genus Trimeresurus) of South-East Asia: bites by T. albolabris and T. macrops in Thailand and a review of the literature.
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Clinical implications of differential antivenom efficacy in neutralising coagulotoxicity produced by venoms from species within the arboreal viperid snake genus Trimeresurus.
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Expression and characterization of a recombinant fibrinogenolytic serine protease from green pit viper (Trimeresurus albolabris) venom.
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The studies on the morphology of lesions produced and the blood coagulation disturbances after Russell viper envenomation were studied in guinea pigs and it was inferred that the consumption coagulonathy is the main pathologic change leading to severe bleeding disorders and the death of the animals. Expand
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Although Arvin is known to differ from ;reptilase' from Bothrops jararaca in that it does not activate the enzyme that cross-links fibrin (fibrin-stabilizing factor), it is identical with reptilase with respect to the peptides that it liberates from fibr inogen. Expand
A quick and accurate method for the determination of fibronogen in plasma.
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